As GLP-1 medications become increasingly integrated into weight management, understanding their implications for muscle and bone health is essential for practitioners supporting patients through significant weight loss. In this episode, Laurence Katsaras is joined by Professor David Scott, exercise scientist and NHMRC Emerging Leadership Fellow at Deakin University, to explore the latest research on GLP-1 therapies and body composition. They discuss the relationship between weight loss and lean mass reduction, the distinction between muscle loss and changes in muscle composition, and the potential implications for long-term physical function, bone health and fracture risk.

David shares practical, evidence-informed strategies to help practitioners support healthy body composition throughout the weight loss journey. From protein requirements and nutritional considerations to the importance of progressive resistance training, he outlines how specialised exercise prescription can help minimise muscle and bone loss. The conversation also explores accessible clinical tools for monitoring body composition and physical function, strategies for supporting sustainable behaviour change, and the opportunities for practitioners to provide individualised lifestyle support. Discover how integrating targeted nutrition, exercise and ongoing monitoring can help patients achieve healthier, more sustainable outcomes while using GLP-1 therapies.