Renee Grandi - The Glymphatic System - A Missing Link in Neurodegenerative Disease

In this episode, we dive deep into one of the brain's most fascinating and overlooked systems - the glymphatic system. Joining us is naturopath and neuroscientist Renée Grandi who unpacks the science of how the brain clears waste, why this process is vital for healthy cognition, and what happens when it falters. She sheds light on the link between glymphatic dysfunction and neurodegenerative conditions such as Alzheimer's, Parkinson's, and MS.

Renée discusses why sleep is so critical for brain detoxification, how chronic inflammation can undermine this delicate system over time, and the integrative strategies - from nutrients and antioxidants to key herbs and lifestyle practices - that can help keep the glymphatic system functioning optimally.

Bio:

Renée Grandi is a neuroscience researcher, naturopath, and clinical nutritionist with over a decade of experience across scientific research, clinical practice, and functional medicine. She specialises in complex chronic illness, neuroimmunology, and integrative women's health, with a focus on conditions that are often dismissed or poorly understood.

Her work explores the connections between the glymphatic system, neuroinflammation, immune dysfunction, and hormonal imbalance, shedding light on the mechanisms driving neurodegenerative disease, autoimmune conditions, and chronic fatigue. Renée bridges the gap between research and integrative care, helping practitioners and patients alike understand how the brain, body, and biology are interconnected - and how this knowledge can be translated into more personalised and effective approaches to health.