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Stress, Toxicity and Mitochondrial Health

Stress and toxicity are common causes of fatigue due to their impact on our mitochondria.1,2

Meeting the higher energy requirements of stress-induced oxidative reactivity is dealt with at a cellular level and involves mitochondrial sustainability. The processes involved include our neuroendocrine hormones and transmitters which affect mitochondrial energetics and well-being.1

Mitochondria play a significant role in our metabolic activity, and are highly vulnerable to being damaged from stress, environmental toxins, and other causes of oxidative damage in our bodies.2

Prolonged energy production demand on our mitochondria can result in DNA instability, increased production of reactive oxygen species, and impairment of our metabolic recovery.4 Our inner cellular environment, in particular our mitochondrial ‘electrical powerplant’ eventually impacts our energy levels, and the lifespan and survival of the cell.1,3


Practitioners, register for access to download:


We also have a webinar with Dr Elizabeth Steels discussing this topic.


This post is educational content for practitioners only. 

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Posts from Integria

Patient Education Series - The Gut Connection: Diet, Digestion and Microbiome

In this episode, Sam Cartwright explores the pivotal role of the gut in maintaining whole-body health, examining digestion as a dynamic, multi-system process rather than a simple breakdown of food. Sam explains how compromised gut function can contribute to systemic issues, from inflammation and immune dysregulation to mood imbalances and chronic disease. Through a functional lens, Sam discusses the integrity of the gut barrier, the clinical relevance of leaky gut, and the impact of the microbiome on broader physiological processes. Sam also clarifies the distinctions between food allergies and intolerances, as well as highlights the influence of the gut-brain axis—emphasising how stress and emotional wellbeing can shape digestive outcomes and chronic health. Discover how evidence-based nutrition and lifestyle strategies can complement your practitioner’s recommendations, to support you in optimising digestive function and uncover the powerful connection between your gut and your whole-body health.
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